Copper alters the defenses against Alzheimer’s disease: the discovery of researchers at the University of Rochester
According to a study conducted by researchers at the University of Rochester, in the U.S., and published in the Proceedings of the National Academy of Sciences , the copper – taken daily through what we eat, such as water coming from the aqueducts or fruits and vegetables – prevent the removal of beta amyloid , the toxic protein that, choking neurons, because the ‘ Alzheimer’s . This metal also alter the defenses against this debilitating neurodegenerative disease also promoting the assembly of the same protein harmful.
More precisely, the copper alters the human defenses against Alzheimer’s tampering with the operation of a protein “scavenger” – the protein receptor-related protein 1 (LRP1) – and its biochemical pathways. The protein LRP1 , which is located inside of the capillaries, which will feed the brain, has the function of releasing this organ from the dross of beta amyloid and prevents the formation of plaques which interrupt the communication between neurons. “It is clear – says one of the authors of the study – which, over time, the ‘ cumulative effect of copper is to impair the systems that beta amyloid plaque is removed from the brain. ”
To reach the conclusion that copper alters the defenses against Alzheimer’s disease, favoring the progression of the disease, scientists have conducted some experiments on lab rats. In particular, it was made to drink to the animals drinking water with a concentration of this metal less than that established by the authorities as permitted limit. Despite this caution, however, it was found that the levels of this substance registered disturb the cleaning action of LRP1 against the toxic protein beta amyloid, in certain cases even favoring aggregation.
Thanks to another research, however, it has been discovered – by examining mice with a physiological predisposition to disease dell ‘ Alzheimer – that copper goes to settle in the capillary wall , so as to impede the passage through the blood-brain barrier , which allows the exchange of substances and molecules to brain tissue and in this way it also protects against viruses and infections.